

MK-677
Ibutamoren · GHS. Supplied in 25 mg vials, lyophilised and ready to reconstitute.
2 more vials to save 5%
Peptides ship as dry powder — you’ll need this to reconstitute the vial.
For laboratory research use only. Not for human or animal consumption, and not a drug, food, or cosmetic. Sold to qualified researchers and institutions.
About MK-677
- Molecular weight
- 528.7 g/mol
- CAS number
- 159634-47-6
MK-677 (ibutamoren) is a non-peptide, orally active small molecule built on a spiroindoline-piperidine scaffold that acts as an agonist of the growth hormone secretagogue receptor (GHS-R1a, the ghrelin receptor). It is used as a research tool compound for studies of ghrelin-receptor signalling.
For laboratory research use only. Not for human or veterinary use.
Specifications
- Sequence
- not recorded
- Molecular formula
- C27H36N4O5S
- Molecular weight
- 528.7 g/mol
- CAS number
- 159634-47-6
- Form
- Lyophilised powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in bacteriostatic or sterile water
- Storage
- Store the lyophilised powder at -20°C, protected from light. Refrigerate reconstituted material at 2 to 8°C and use within its stability window.
- Purity
- 99.5%
- Lot
- PX-2414-A
- Test date
- May 2026
- Testing lab
- third-party
- Methods
- HPLC, LC-MS/MS
Certificate
Handling and storage
Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.
Literature
- Design and biological activities of L-163,191 (MK-0677), a potent, orally active growth hormone secretagoguePatchett AA, et al. · PNAS · 1995
Common questions about MK-677
- What is MK-677?
- MK-677 (ibutamoren) is a non-peptide, orally active small molecule built on a spiroindoline-piperidine scaffold that acts as an agonist of the growth hormone secretagogue receptor (GHS-R1a, the ghrelin receptor).
- How is MK-677 supplied?
- MK-677 is supplied as a lyophilised (freeze-dried) powder in 25 mg vials, for laboratory research use only.
- How should MK-677 be stored and handled?
- Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.
- Has this batch of MK-677 been independently tested?
- Yes. Lot PX-2414-A was tested at 99.5% by an independent laboratory. The full certificate of analysis is published and searchable by lot code on the verify page, before and after purchase.
- Is MK-677 for human use?
- No. MK-677 is supplied strictly for in vitro laboratory research. It is not for human or animal consumption, and is not a drug, food, or cosmetic.
Researchers also study
Reconstitution
A measurement aid for laboratory handling. For research use only.
Need the syringe mark, a round-number draw, or a U-40 reading? Open the full calculator with this 25 mg vial loaded.


