Semax

About Semax

Residues

7

Molecular weight

813.9 g/mol

CAS number

80714-61-0

Semax is a synthetic heptapeptide corresponding to the ACTH(4-7) fragment (Met-Glu-His-Phe) extended at the C-terminus with a Pro-Gly-Pro tripeptide, which increases proteolytic stability relative to the native ACTH sequence. In laboratory models it is studied as a melanocortin-related and neurotrophic-signalling-modulating peptide, including reported effects on BDNF/TrkB-associated pathways.

For laboratory research use only. Not for human or veterinary use.

Specifications

Certificate

Handling and storage

Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.

Research note

A synthetic ACTH(4-7) analogue capped with Pro-Gly-Pro for stability. What the preclinical neurochemistry literature examines, and what it does not. Research use only.

Read the full note: Semax: the ACTH fragment engineered to sit still

Literature

Published third-party research on this compound, listed for reference. These are the findings of the cited authors, not claims about the material we supply.

• The peptide ACTH(4-7)PGP (Semax) suppresses proinflammatory mediators after reversible brain ischemia
  Molekuliarnaia Biologiia · 2021

Common questions about Semax

What is Semax?

Semax is a synthetic heptapeptide corresponding to the ACTH(4-7) fragment (Met-Glu-His-Phe) extended at the C-terminus with a Pro-Gly-Pro tripeptide, which increases proteolytic stability relative to the native ACTH sequence.

How is Semax supplied?

Semax is supplied as a lyophilised (freeze-dried) powder in 10 mg and 30 mg vials, for laboratory research use only.

How should Semax be stored and handled?

Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.

Has this batch of Semax been independently tested?

Yes. Lot PX-2422-C was tested at 99.2% by an independent laboratory. The full certificate of analysis is published and searchable by lot code on the verify page, before and after purchase.

Is Semax for human use?

No. Semax is supplied strictly for in vitro laboratory research. It is not for human or veterinary use, and is not a medicine, food, or cosmetic.

Reconstitution

Need the syringe mark, a round-number draw, or a U-40 reading? Open the full calculator with this 10 mg vial loaded.