

MOTS-c
Mitochondrial Peptide. Supplied in 5 and 10 mg vials, lyophilised and ready to reconstitute.
2 more vials to save 5%
Peptides ship as dry powder — you’ll need this to reconstitute the vial.
For laboratory research use only. Not for human or animal consumption, and not a drug, food, or cosmetic. Sold to qualified researchers and institutions.
About MOTS-c
- Residues
- 16
- Molecular weight
- 2174.6 g/mol
- CAS number
- 1627580-64-6
MOTS-c is a 16-residue mitochondrial-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA (MT-RNR1) region. It is studied as a regulator of cellular metabolism, reported to act on the folate-methionine pathway and to activate AMP-activated protein kinase (AMPK) signalling. It is a linear peptide of standard L-amino acids.
For laboratory research use only. Not for human or veterinary use.
Specifications
- Sequence
- MRWQEMGYIFYPRKLR
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.6 g/mol
- CAS number
- 1627580-64-6
- Form
- Lyophilised powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in bacteriostatic or sterile water
- Storage
- Store the lyophilised powder at -20°C, protected from light. Refrigerate reconstituted material at 2 to 8°C and use within its stability window.
- Purity
- 98.7%
- Lot
- PX-2419-C
- Test date
- May 2026
- Testing lab
- third-party
- Methods
- HPLC, LC-MS/MS
Certificate
Handling and storage
Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.
Literature
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces insulin resistanceLee C, et al. · Cell Metabolism · 2015
Common questions about MOTS-c
- What is MOTS-c?
- MOTS-c is a 16-residue mitochondrial-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA (MT-RNR1) region. It is studied as a regulator of cellular metabolism, reported to act on the folate-methionine pathway and to activate AMP-activated protein kinase (AMPK) signalling.
- How is MOTS-c supplied?
- MOTS-c is supplied as a lyophilised (freeze-dried) powder in 5 mg and 10 mg vials, for laboratory research use only.
- How should MOTS-c be stored and handled?
- Reconstitute with bacteriostatic or sterile water. Store the lyophilised powder at -20°C, protected from light; refrigerate reconstituted material at 2 to 8°C. Handle under standard laboratory conditions.
- Has this batch of MOTS-c been independently tested?
- Yes. Lot PX-2419-C was tested at 98.7% by an independent laboratory. The full certificate of analysis is published and searchable by lot code on the verify page, before and after purchase.
- Is MOTS-c for human use?
- No. MOTS-c is supplied strictly for in vitro laboratory research. It is not for human or animal consumption, and is not a drug, food, or cosmetic.
Researchers also study
Reconstitution
A measurement aid for laboratory handling. For research use only.
Need the syringe mark, a round-number draw, or a U-40 reading? Open the full calculator with this 5 mg vial loaded.


